Sr. Bioinformatics Scientist - cfDNA Technology Development Job at Personalis, Inc, Fremont, CA

MHNOM3FRVWVLSkhJOGJFd3JiTlU0REJlZ2c9PQ==
  • Personalis, Inc
  • Fremont, CA

Job Description

Personalis, Inc. is a leader in advanced genomics for precision oncology. NeXT Personal is an ultra-sensitive, tumor-informed, WGS-based liquid biopsy assay designed to detect minimal residual disease (MRD) and cancer recurrence. It leverages whole-genome sequencing of a patient's tumor and matched normal samples to create personalized panel of up to 1,800 somatic variants, enabling the detection of circulating tumor DNA (ctDNA) at very low levels (down to ~1-3 PPM) in blood samples. To enable cancer and population sequencing, Personalis' Clinical Laboratory was built with a focus on clinical accuracy, quality, big data, scale, and efficiency.

Days Onsite: Monday & Tuesday

Summary:

The Bioinformatics Senior Scientist will work with a world-class, dynamic team of bioinformatics scientists, software engineers, and laboratory scientists, developing, testing, and applying cutting-edge cell-free and solid tumor cancer genomics products. Further, the Bioinformatics Scientist will be working alongside our clinical evidence generation teams, applying our cell-free solutions to large cancer patient cohorts and profiling patient response to therapy with our cfDNA platforms. This position will directly contribute to a new generation of genomics-based precision-medicine products for profiling MRD, ctDNA dynamics, and patient response to treatment. Our products are used by pharma, biotech, hospitals, and clinicians for managing patient treatment and therapeutic selection.

Responsibilities:
  • Design, develop, and build upon our novel cell-free platforms and products, including our NeXT Personal MRD liquid biopsy platform
  • Work cross-functionally to translate collaborative findings into actively developed cutting-edge products
  • Design and execute scientific projects and experiments focused on product feature feasibility, demonstrating feature performance and clinical advantages of our cell-free platforms
  • Modeling and analysis of large, complex genomics datasets using novel methods to generate biological insights
  • Work with scientific teams to translate scientific findings into actively developed groundbreaking products
  • Publish results and present at conferences in exciting areas, including cell-free DNA and cancer genomics


Requirements:

  • Advanced degree (Ph.D.) in bioinformatics, genomics, or a related field
  • Extensive experience with cancer genomics
  • Extensive experience with somatic mutational detection and filtering
  • Experience with cancer liquid biopsy analysis
  • Proficiency with at least one common programming language (e.g., Python, R)
  • A track record of designing and implementing experimental approaches to confirm and elaborate upon findings from complex projects
  • Experience publishing and presenting scientific results


The hiring range for this position is$155,000 to $190,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.

Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @ personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.

Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)

#LI-KK1 #LI-Hybrid

Job Tags

Full time

Similar Jobs

ARGO

Retail Banking Solution Specialist Job at ARGO

 ...breakthrough technology, and rich analytics. JOB SUMMARY A Retail Banking Solution Specialists role is to execute go-to-market...  ...should have a good balance of knowledge in areas such as: Back-office deposit operations Customer identity and authentication... 

Globe Life AIL - Lisa Russel

Customer Service Representative - ONLINE Job at Globe Life AIL - Lisa Russel

 ...Remote Services Representative Make a Difference Location: 100% Remote Schedule: Flexible Are you looking for a work-from-home opportunity where you can grow your career, help others, and uphold the highest standards of integrity? AO is seeking dedicated... 

Cigna

Billing & Reimbursement Senior Representative - Whitestown, Indiana Job at Cigna

POSITION SUMMARY: Join our team our Accounts Receivable team that supports our Specialty Pharmacy - Accredo, as a Billing & Reimbursement Representative . In this role, you will utilize advanced knowledge to prepare and review claims approaching timely filing to...

Confidential

Offer: Instructional Designer Job at Confidential

 ...Instructional Designer The instructional designerwill be a memberof thedesign teamin the Instructional Design and Development unit at Excelsior University. Our team works closely with subject matter experts and other community and university stakeholders to develop... 

ScaleHouse Talent

In-Home Sales Representative Job at ScaleHouse Talent

 ...backed by a strong national brand and a locally driven team. Our Dallas Fort Worth division is growing and hiring due to expansion, creating a rare opportunity to join a high-tenure sales organization. As an In-Home Sales Representative, you will run preset, qualified a